LDN treatment involves using the medication naltrexone in very small doses to regulate the immune system and reduce inflammation.
In order to understand low-dose naltrexone (LDN), it’s important to look at the traditional use of naltrexone. Naltrexone is a medication that has great success as part of a complete treatment program for drug and alcohol addictions. It works by blocking the “high” created by
opiates or alcohol, which curbs the urge to use again. It does this without any narcotic effect.
Because naltrexone blocks the receptors for opioids, your body increases production of endorphins to compensate. Endorphins have anti-inflammatory properties, so naltrexone also reduces inflammation.
Treatment with low-dose naltrexone leverages those benefits through a low dose, typically about 1/10 of a traditional dose. A surprisingly wide range of conditions can benefit from LDN.
Healthcare practitioners continue to find more uses for LDN therapy. It’s particularly effective for autoimmune conditions or conditions characterized by pain. Some of the primary uses for LDN are:
At higher doses, naltrexone is associated with several side effects, particularly damage to the liver. However, the dosages for LDN treatment are so low that most patients don’t experience any adverse effects at all. A small number have reported difficulty sleeping, more vivid dreams, nausea, and diarrhea, but when necessary, the dose of naltrexone can be reduced further to alleviate side effects.
Just reach out and jump on a free strategy call with Cherise to find out how LDN can be a
part of your holistic treatment plan!
Sources:
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O’Kelly B, Vidal L, McHugh T, Woo J, Avramovic G, Lambert JS. Safety and efficacy of low dose naltrexone in a long covid cohort; an interventional pre-post study. Brain Behav Immune Health. 2022 Oct;24:100485. doi: 10.1016/j.bbih.2022.100485. Epub 2022 Jul 3. PMID: 35814187; PMCID: PMC9250701.
What Patients Say Works for Fibromyalgia, 23andMe, https://blog.23andme.com/23andme-research/what-patients-say-works-for-fibromyalgia/
Couto RD, Fernandes BJD. Low Doses Naltrexone: The Potential Benefit Effects for its Use in Patients with Cancer. Curr Drug Res Rev. 2021;13(2):86-89. doi: 10.2174/2589977513666210127094222. PMID: 33504322.
Teneralli RE, Kern DM, Cepeda MS, Gilbert JP, Drevets WC. Exploring real-world evidence to uncover unknown drug benefits and support the discovery of new treatment targets for depressive and bipolar disorders. J Affect Disord. 2021 Jul 1;290:324-333. doi: 10.1016/j.jad.2021.04.096. Epub 2021 May 2. PMID: 34020207.
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